lower extremity arterial calcification as a predictor of coronary atherosclerosis in patients with peripheral arterial disease
نویسندگان
چکیده
conclusion peripheral arterial calcification is significantly correlated with cad extent in patients with pad. peripheral arterial calcification can be a useful marker for predicting multivessel-cad. results lecs in multivessel-cad were significantly higher than those in nonsignificant cad (10.0 ± 5.8 versus 4.0 ± 3.1, p < 0.001). lecs significantly correlated with ccs (r = 0.831, p < 0.001) and the extent of cad (r = 0.631, p < 0.001). multivariate regression analysis demonstrated lecs and log-transformed ccs were independent predictors for multivessel-cad. in receiver operating characteristic curve analysis, the diagnostic performance of lecs was 0.807 (95% confidence interval = 0.724-0.891, p < 0.001) for predicting multivessel-cad. background until now, there has been no study on the relationship between the calcification of the lower extremity arteries and significant coronary arterial disease (cad). objectives to evaluate whether lower extremity calcium scores (lecs) are associated with cad and whether this can predict multivessel-cad in patients with peripheral arterial disease (pad). patients and methods we retrospectively enrolled 103 pad patients without cardiac symptoms or known cad. all patients underwent cardiac computed tomography (ct) and lower extremity ct within 1 month and were categorized as nonsignificant cad, single-cad, or multivessel-cad. the coronary calcium scores (ccs) were quantitatively measured according to the agatston method and lecs were semi-quantitatively measured according to the presence of lower extremity calcification in the segment. the extent of cad was evaluated according to the presence of ≥ 50% luminal diameter stenosis in the segment of cad.
منابع مشابه
Lower Extremity Arterial Calcification as a Predictor of Coronary Atherosclerosis in Patients with Peripheral Arterial Disease
BACKGROUND Until now, there has been no study on the relationship between the calcification of the lower extremity arteries and significant coronary arterial disease (CAD). OBJECTIVES To evaluate whether lower extremity calcium scores (LECS) are associated with CAD and whether this can predict multivessel-CAD in patients with peripheral arterial disease (PAD). PATIENTS AND METHODS We retros...
متن کاملLower Extremity Peripheral Arterial Disease
Eight to 12 million people in United States have PAD (Allison et al. 2007). Only ~10% of patients with PAD have classic intermittent claudication (IC), ~50% have atypical leg symptoms and ~40% are asymptomatic (Hiatt 2001). Its prevalence significantly increases with age; 12 – 20% of those above the age of 65 years suffer from PAD (Ostchega al. 2007). The prevalence of PAD is similar in men and...
متن کاملPrevalence of Peripheral Arterial Disease in Diabetic Patients
Objective: Peripheral Arterial Disease (PAD) is a state characterized by atherosclerotic occlusive disease of lower extremities. Diabetes is the main risk factor for PAD. Material and Methods: To assess the prevalence of PAD, a cross sectional study was performed on 352 diabetic patients who referred to Yazd diabetes research center from 2007 to 2010. Vascular assessment was done by measuring ...
متن کاملAssociation of Lower Extremity Arterial Calcification with Amputation and Mortality in Patients with Symptomatic Peripheral Artery Disease
OBJECTIVE The clinical implication of the coronary artery calcium score (CS) is well demonstrated. However, little is known about the association between lower extremity arterial calcification and clinical outcomes. METHODS AND RESULTS Eighty-two patients with symptomatic peripheral artery disease (age 61.0±12.4 years) were followed for 21±11 months. CSs, ranging from the common iliac artery ...
متن کاملLong‐Term Prognostic Risk in Lower Extremity Peripheral Arterial Disease as a Function of the Number of Peripheral Arterial Lesions
BACKGROUND Although patients with peripheral artery disease (PAD) are known to have an increased risk of adverse prognosis, simple techniques to further risk-stratify PAD patients would be clinically useful. A plausible but unexplored factor to predict such risk would be greater disease burden, manifested as multiple lower extremity lesions. The aim of this study was to examine the association ...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian journal of radiologyجلد ۱۳، شماره ۲، صفحات ۰-۰
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023